Human Retroviruses (frontiers In Molecular Biology)

Introduction To Human Retroviruses / Bryan R. Cullen -- Retroviral Replication Cycle -- Retroviral Taxonomy -- Biological And Molecular Basis For Cell Tropism In Hiv / Vicente Planelles, Qi-xiang Li And Irvin S.y. Chen -- Genetic Variation Of Hiv -- Species Specificity Of Hiv -- Tissue Distribution Of Hiv -- Cd4 Glycoprotein Is The Major Receptor For Hiv -- Structure Of The Hiv Envelope Glycoprotein -- Tropism Of The Aids Virus: Historical Perspective -- V3 Loop As A Determinant Of Tropism -- Envelope Regions Other Than V3 May Be Involved In Tropism -- Regions Other Than Envelope May Also Control Tropism -- Tropism For Other Cell Types -- Mechanisms -- Role Of Cellular Transcription Factors In The Regulation Of Human Immunodeficiency Virus Gene Expression / Gary J. Nabel -- Rna Polymerases And Associated Transcription Factors -- Transcriptional Regulatory Proteins And The Hiv Promoter -- Inducible Gene Expression And The Hiv Enhancer -- Negative Regulation Of The Hiv Enhancer -- Nf-kb Family Of Transcriptional Activators -- Regulation Of Nf-kb By Ikb. (cont) Anti-oxidants And The Regulation Of Hiv Transcription -- Macrophage Regulation Of Hiv Expression -- Transcriptional Regulation Of Hiv-2 -- Tat Trans-activator / B. Matija Peterlin [and Others] -- Tat Trans-activator -- Trans-activation Response Element, Tar -- Mechanisms Of Trans-activation By Tat -- Tat And The Hiv Life Cycle -- Other Effects Of Tat -- Post-transcriptional Regulation Of Human Retroviral Gene Expression / Tristram G. Parslow -- Alternative Splicing Of Retroviral Rnas -- Post-transcriptional Trans-activation Of Complex Retroviruses -- Translation Of Retroviral Mrnas -- Potential Targets For Antiretroviral Therapy -- Auxiliary Proteins Of The Primate Immunodeficiency Viruses / James S. Gibbs And Ronald C. Desrosiers -- Vif -- Vpr -- Vpx -- Vpu -- Nef -- Molecular Biology Of Human T-cell Leukemia Viruses / Scott D. Gitlin [and Others] -- Htlv Genome Structure -- Transformation -- Epidemiology -- Htlv-associated Diseases -- Tax Structure And Functional Domains -- Rex -- P21(x-iii) -- Transcriptional Regulation Of Htlv Gene Expression. (cont) Tax Trans-activation Of Cellular Genes -- Extracellular Cytokine Effects Of Tax -- Molecular Biology Of The Human Spumavirus / Rolf M. Flugel -- Morphological And Virological Properties Of Spumaviruses -- Overview Of The Replication Cycle Of Hsrv In Comparison With Other Retroviruses -- Genetic Structure Of Hsrv Is Complex -- Transcriptional Pattern Of The Hsrv Genome Is Complex -- Bel 1 Is The Hsrv Transcriptional Trans-activator -- Hsrv Ltr Is Unusually Long And Contains Different Dna Response Elements For The Trans-activator Bel 1 -- Is Bel 3 A Spumaviral Superantigen? -- Hsrv-specific Detection Systems -- Sero-epidemiological Studies On Prevalence Of Hsrv Antibodies -- Neuropathogenicity Of Hsrv Genes In Transgenic Mice. Edited By Bryan R. Cullen. Includes Bibliographical References And Index.